Explored new potentials for protein folding using various machine learning methods
Created analysis tools to assess changes in simulated folding kinetics due to point mutations
Created protocols to identify binding conformations of amino acids to various mineral surface models
Developed Monte Carlo simulations to generate canonical ensembles of bound conformations
Applied statistical mechanics and binding models to connect empirical AFM data to computational results
Tabrizi K.R., Pacella M.S., Gray J.J. Computation of Amino Acid-Mineral Surface Interaction
Thermodynamics via Detailed-Balance Sampling in Rosetta. Manuscript in preparation.
Presented a talk on my work at the 2017 AIChE Annual Meeting in Minnesota
Received undergraduate research funding through the Elenora Streb Muly Award
Studied the applications of microwave radiation and clay catalysts in organic syntheses
Applied analytical techniques, including gas chromatography, mass spectrometry, and NMR
Performed vacuum and separatory filtrations, distillations, and other basic techniques
Prepared reflux condensation apparatuses, solutions, basifications, and other techniques
Produced a final paper and presentation outlining our experiment and its results (
available here)
Amplified DNA through PCR to identify genotypes
Performed restriction digests, ligations, transformations, and plasmid preps
Gained experience with immunohistochemistry, Western blots, and ELISAs
Conducted serial dilutions, Bradford Assays, and gel electrophoresis
Practiced growing bacterial cultures, pipetting, centrifugation, and other techniques
Ran graphical and statistical data analysis, implemented NIH's BLAST databases
Created a research paper detailing the experiment and reviewing relevant literature
Produced a presentation outlining the experimental methods, results, and conclusions